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Striatal phosphodiesterase 10A and medial prefrontal cortical thickness in patients with schizophrenia: a PET and MRI study

The enzyme phosphodiesterase 10A (PDE10A) is abundant in striatal medium spiny neurons and has been implicated in the pathophysiology of schizophrenia in animal models and is investigated as a possible new pharmacological treatment target. A reduction of prefrontal cortical thickness is common in sc...

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Detalles Bibliográficos
Autores principales:	Bodén, R, Persson, J, Wall, A, Lubberink, M, Ekselius, L, Larsson, E-M, Antoni, G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416662/ https://www.ncbi.nlm.nih.gov/pubmed/28267149 http://dx.doi.org/10.1038/tp.2017.11

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