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Depletion of adult neurogenesis using the chemotherapy drug temozolomide in mice induces behavioural and biological changes relevant to depression

Numerous studies have examined links between postnatal neurogenesis and depression using a range of experimental methods to deplete neurogenesis. The antimitotic drug temozolomide (TMZ) has previously been used successfully as an experimental tool in animals to deplete adult neurogenesis and is used...

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Detalles Bibliográficos
Autores principales: Egeland, M, Guinaudie, C, Du Preez, A, Musaelyan, K, Zunszain, P A, Fernandes, C, Pariante, C M, Thuret, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416706/
https://www.ncbi.nlm.nih.gov/pubmed/28440814
http://dx.doi.org/10.1038/tp.2017.68