Short telomere length is associated with impaired cognitive performance in European ancestry cohorts

The association between telomere length (TL) dynamics on cognitive performance over the life-course is not well understood. This study meta-analyses observational and causal associations between TL and six cognitive traits, with stratifications on APOE genotype, in a Mendelian Randomization (MR) fra...

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Detalles Bibliográficos
Autores principales: Hägg, S, Zhan, Y, Karlsson, R, Gerritsen, L, Ploner, A, van der Lee, S J, Broer, L, Deelen, J, Marioni, R E, Wong, A, Lundquist, A, Zhu, G, Hansell, N K, Sillanpää, E, Fedko, I O, Amin, N A, Beekman, M, de Craen, A J M, Degerman, S, Harris, S E, Kan, K-J, Martin-Ruiz, C M, Montgomery, G W, Adolfsson, A N, Reynolds, C A, Samani, N J, Suchiman, H E D, Viljanen, A, von Zglinicki, T, Wright, M J, Hottenga, J-J, Boomsma, D I, Rantanen, T, Kaprio, J A, Nyholt, D R, Martin, N G, Nyberg, L, Adolfsson, R, Kuh, D, Starr, J M, Deary, I J, Slagboom, P E, van Duijn, C M, Codd, V, Pedersen, N L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416710/
https://www.ncbi.nlm.nih.gov/pubmed/28418400
http://dx.doi.org/10.1038/tp.2017.73

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