Efficient mapping of transgene integration sites and local structural changes in Cre transgenic mice using targeted locus amplification

Cre/LoxP technology is widely used in the field of mouse genetics for spatial and/or temporal regulation of gene function. For Cre lines generated via pronuclear microinjection of a Cre transgene construct, the integration site is random and in most cases not known. Integration of a transgene can di...

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Detalles Bibliográficos
Autores principales: Cain-Hom, Carol, Splinter, Erik, van Min, Max, Simonis, Marieke, van de Heijning, Monique, Martinez, Maria, Asghari, Vida, Cox, J. Colin, Warming, Søren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416772/
https://www.ncbi.nlm.nih.gov/pubmed/28053125
http://dx.doi.org/10.1093/nar/gkw1329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416772/
https://www.ncbi.nlm.nih.gov/pubmed/28053125
http://dx.doi.org/10.1093/nar/gkw1329

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