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Efficient mapping of transgene integration sites and local structural changes in Cre transgenic mice using targeted locus amplification
Cre/LoxP technology is widely used in the field of mouse genetics for spatial and/or temporal regulation of gene function. For Cre lines generated via pronuclear microinjection of a Cre transgene construct, the integration site is random and in most cases not known. Integration of a transgene can di...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416772/ https://www.ncbi.nlm.nih.gov/pubmed/28053125 http://dx.doi.org/10.1093/nar/gkw1329 |