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PRMT5 regulates IRES-dependent translation via methylation of hnRNP A1

The type II arginine methyltransferase PRMT5 is responsible for the symmetric dimethylation of histone to generate the H3R8me2s and H4R3me2s marks, which correlate with the repression of transcription. However, the protein level of a number of genes (MEP50, CCND1, MYC, HIF1a, MTIF and CDKN1B) are re...

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Detalles Bibliográficos
Autores principales:	Gao, Guozhen, Dhar, Surbhi, Bedford, Mark T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416833/ https://www.ncbi.nlm.nih.gov/pubmed/28115626 http://dx.doi.org/10.1093/nar/gkw1367

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