Cargando…

In vivo cleavage specificity of Trypanosoma brucei editosome endonucleases

RNA editing is an essential post-transcriptional process that creates functional mitochondrial mRNAs in Kinetoplastids. Multiprotein editosomes catalyze pre-mRNA cleavage, uridine (U) insertion or deletion, and ligation as specified by guide RNAs. Three functionally and compositionally distinct edit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carnes, Jason, McDermott, Suzanne, Anupama, Atashi, Oliver, Brian G., Sather, D. Noah, Stuart, Kenneth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416837/ https://www.ncbi.nlm.nih.gov/pubmed/28334821 http://dx.doi.org/10.1093/nar/gkx116

Ejemplares similares

RNase III Domain of KREPB9 and KREPB10 Association with Editosomes in Trypanosoma brucei
por: Carnes, Jason, et al.
Publicado: (2018)

Increasing cleavage specificity and activity of restriction endonuclease KpnI
por: Vasu, Kommireddy, et al.
Publicado: (2013)

Catalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificities
por: Chan, Siu-hong, et al.
Publicado: (2007)

Centromere-associated topoisomerase activity in bloodstream form Trypanosoma brucei
por: Obado, Samson O., et al.
Publicado: (2011)

Editosome RNase III domain interactions are essential for editing and differ between life cycle stages in Trypanosoma brucei
por: McDermott, Suzanne M., et al.
Publicado: (2019)

Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases
por: Macíčková-Cahová, Hana, et al.
Publicado: (2009)

Rational engineering of type II restriction endonuclease DNA binding and cleavage specificity
por: Morgan, Richard D., et al.
Publicado: (2009)

A ribosome profiling study of mRNA cleavage by the endonuclease RelE
por: Hwang, Jae-Yeon, et al.
Publicado: (2017)

Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases
por: McMurrough, Thomas A, et al.
Publicado: (2018)

Flow cytometric analysis of DNA binding and cleavage by cell surface-displayed homing endonucleases
por: Volná, Petra, et al.
Publicado: (2007)

BspRI restriction endonuclease: cloning, expression in Escherichia coli and sequential cleavage mechanism
por: Raskó, Tamás, et al.
Publicado: (2010)

Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease
por: Horton, John R., et al.
Publicado: (2012)

Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering
por: Ulge, Umut Y., et al.
Publicado: (2011)

Functional characterization of a 48 kDa Trypanosoma brucei cap 2 RNA methyltransferase
por: Hall, Megan P., et al.
Publicado: (2006)

Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage
por: Josephs, Eric A., et al.
Publicado: (2015)

Perpetuating the homing endonuclease life cycle: identification of mutations that modulate and change I-TevI cleavage preference
por: Roy, Alexander C., et al.
Publicado: (2016)

Site specific target binding controls RNA cleavage efficiency by the Kaposi's sarcoma-associated herpesvirus endonuclease SOX
por: Mendez, Aaron S, et al.
Publicado: (2018)

A novel endonuclease activity associated with the Arabidopsis ortholog of the 30-kDa subunit of cleavage and polyadenylation specificity factor
por: Addepalli, Balasubrahmanyam, et al.
Publicado: (2007)

Mechanism of DNA cleavage by the endonuclease SauUSI: a major barrier to horizontal gene transfer and antibiotic resistance in Staphylococcus aureus
por: Tumuluri, Vinayak Sadasivam, et al.
Publicado: (2021)

Natural zinc ribbon HNH endonucleases and engineered zinc finger nicking endonuclease
por: Xu, Shuang-yong, et al.
Publicado: (2013)

The Mus81-Mms4 structure-selective endonuclease requires nicked DNA junctions to undergo conformational changes and bend its DNA substrates for cleavage
por: Mukherjee, Sucheta, et al.
Publicado: (2014)

Single-site DNA cleavage by Type III restriction endonuclease requires a site-bound enzyme and a trans-acting enzyme that are ATPase-activated
por: Ahmad, Ishtiyaq, et al.
Publicado: (2018)

Dynamics and consequences of DNA looping by the FokI restriction endonuclease
por: Catto, Lucy E., et al.
Publicado: (2008)

Creating highly specific nucleases by fusion of active restriction endonucleases and catalytically inactive homing endonucleases
por: Fonfara, Ines, et al.
Publicado: (2012)

Endonuclease domain of non-LTR retrotransposons: loss-of-function mutants and modeling of the R2Bm endonuclease
por: Govindaraju, Aruna, et al.
Publicado: (2016)

Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands
por: Sanders, Kelly L., et al.
Publicado: (2009)

A hexanucleotide sequence (dC(1)–dC(6) tract) restricts the dC-specific cleavage of single-stranded DNA by endonuclease IV of bacteriophage T4
por: Ohshima, Hiroyuki, et al.
Publicado: (2007)

The essential functions of KREPB4 are developmentally distinct and required for endonuclease association with editosomes
por: McDermott, Suzanne M., et al.
Publicado: (2017)

Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation
por: Takeuchi, Ryo, et al.
Publicado: (2009)

The Ser(176) of T4 endonuclease IV is crucial for the restricted and polarized dC-specific cleavage of single-stranded DNA implicated in restriction of dC-containing DNA in host Escherichia coli
por: Hirano, Nobutaka, et al.
Publicado: (2007)

Thermodynamics of DNA target site recognition by homing endonucleases
por: Eastberg, Jennifer H., et al.
Publicado: (2007)

Type I restriction endonucleases are true catalytic enzymes
por: Bianco, Piero R., et al.
Publicado: (2009)

Characterization of the 5-hydroxymethylcytosine-specific DNA restriction endonucleases
por: Borgaro, Janine G., et al.
Publicado: (2013)

Massively parallel determination and modeling of endonuclease substrate specificity
por: Thyme, Summer B., et al.
Publicado: (2014)

Restriction glycosylases: involvement of endonuclease activities in the restriction process
por: Zhang, Yingbiao, et al.
Publicado: (2017)

EXOG, a novel paralog of Endonuclease G in higher eukaryotes
por: Cymerman, Iwona A., et al.
Publicado: (2008)

Concerted action at eight phosphodiester bonds by the BcgI restriction endonuclease
por: Marshall, Jacqueline J. T., et al.
Publicado: (2011)

Pso2 (SNM1) is a DNA structure-specific endonuclease
por: Tiefenbach, Tracy, et al.
Publicado: (2012)

Rational engineering of sequence specificity in R.MwoI restriction endonuclease
por: Skowronek, Krzysztof, et al.
Publicado: (2012)

A unique family of Mrr-like modification-dependent restriction endonucleases
por: Zheng, Yu, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ff8f5r7qk1p97g97146eujbmrc