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Sustained expression of miR-26a promotes chromosomal instability and tumorigenesis through regulation of CHFR
MicroRNA 26a (miR-26a) reduces cell viability in several cancers, indicating that miR-26a could be used as a therapeutic option in patients. We demonstrate that miR-26a not only inhibits G1-S cell cycle transition and promotes apoptosis, as previously described, but also regulates multiple cell cycl...
Autores principales: | Castellano, Leandro, Dabrowska, Aleksandra, Pellegrino, Loredana, Ottaviani, Silvia, Cathcart, Paul, Frampton, Adam E., Krell, Jonathan, Stebbing, Justin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416844/ https://www.ncbi.nlm.nih.gov/pubmed/28126920 http://dx.doi.org/10.1093/nar/gkx022 |
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