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Long non-coding RNAs transcribed by ERV-9 LTR retrotransposon act in cis to modulate long-range LTR enhancer function

LTR retrotransposons are repetitive DNA elements comprising ∼10% of the human genome. However, LTR sequences are disproportionately present in human long, non-coding RNAs (lncRNAs). Whether and how the LTR lncRNAs serve biological functions are largely unknown. Here we show that in primary human ery...

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Detalles Bibliográficos
Autores principales:	Hu, Tianxiang, Pi, Wenhu, Zhu, Xingguo, Yu, Miao, Ha, Hongseok, Shi, Huidong, Choi, Jeong-Hyeon, Tuan, Dorothy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416847/ https://www.ncbi.nlm.nih.gov/pubmed/28132025 http://dx.doi.org/10.1093/nar/gkx055

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