C5-substituents of uridines and 2-thiouridines present at the wobble position of tRNA determine the formation of their keto-enol or zwitterionic forms - a factor important for accuracy of reading of guanosine at the 3΄-end of the mRNA codons

Modified nucleosides present in the wobble position of the tRNA anticodons regulate protein translation through tuning the reading of mRNA codons. Among 40 of such nucleosides, there are modified uridines containing either a sulfur atom at the C2 position and/or a substituent at the C5 position of t...

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Detalles Bibliográficos
Autores principales: Sochacka, Elzbieta, Lodyga-Chruscinska, Elzbieta, Pawlak, Justyna, Cypryk, Marek, Bartos, Paulina, Ebenryter-Olbinska, Katarzyna, Leszczynska, Grazyna, Nawrot, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416851/
https://www.ncbi.nlm.nih.gov/pubmed/28088758
http://dx.doi.org/10.1093/nar/gkw1347

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