Mechanistic insights into type I toxin antitoxin systems in Helicobacter pylori: the importance of mRNA folding in controlling toxin expression

Type I toxin-antitoxin (TA) systems have been identified in a wide range of bacterial genomes. Here, we report the characterization of a new type I TA system present on the chromosome of the major human gastric pathogen, Helicobacter pylori. We show that the aapA1 gene encodes a 30 amino acid peptid...

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Detalles Bibliográficos
Autores principales: Arnion, Hélène, Korkut, Dursun Nizam, Masachis Gelo, Sara, Chabas, Sandrine, Reignier, Jérémy, Iost, Isabelle, Darfeuille, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416894/
https://www.ncbi.nlm.nih.gov/pubmed/28077560
http://dx.doi.org/10.1093/nar/gkw1343

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