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Determination of the conformational ensemble of the TAR RNA by X-ray scattering interferometry

The conformational ensembles of structured RNA's are crucial for biological function, but they remain difficult to elucidate experimentally. We demonstrate with HIV-1 TAR RNA that X-ray scattering interferometry (XSI) can be used to determine RNA conformational ensembles. X-ray scattering inter...

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Detalles Bibliográficos
Autores principales: Shi, Xuesong, Walker, Peter, Harbury, Pehr B., Herschlag, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416899/
https://www.ncbi.nlm.nih.gov/pubmed/28108663
http://dx.doi.org/10.1093/nar/gkw1352