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Determination of the conformational ensemble of the TAR RNA by X-ray scattering interferometry
The conformational ensembles of structured RNA's are crucial for biological function, but they remain difficult to elucidate experimentally. We demonstrate with HIV-1 TAR RNA that X-ray scattering interferometry (XSI) can be used to determine RNA conformational ensembles. X-ray scattering inter...
Autores principales: | Shi, Xuesong, Walker, Peter, Harbury, Pehr B., Herschlag, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416899/ https://www.ncbi.nlm.nih.gov/pubmed/28108663 http://dx.doi.org/10.1093/nar/gkw1352 |
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