RAD51 interconnects between DNA replication, DNA repair and immunity

RAD51, a multifunctional protein, plays a central role in DNA replication and homologous recombination repair, and is known to be involved in cancer development. We identified a novel role for RAD51 in innate immune response signaling. Defects in RAD51 lead to the accumulation of self-DNA in the cyt...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Souparno, Srinivasan, Kalayarasan, Abdisalaam, Salim, Su, Fengtao, Raj, Prithvi, Dozmorov, Igor, Mishra, Ritu, Wakeland, Edward K., Ghose, Subroto, Mukherjee, Shibani, Asaithamby, Aroumougame
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416901/
https://www.ncbi.nlm.nih.gov/pubmed/28334891
http://dx.doi.org/10.1093/nar/gkx126

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