Cargando…
Delayed Effects of Transcutaneous Organophosphate Poisoning in Four Children
Contamination or transcutaneous absorption of organophosphates (OP) is rare and there exist only few reports of such manner of poisoning. We report four children from the same family in whom temporal proximity of the disease onset, a detailed interrogation of parents and exclusion of other clinical...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417017/ https://www.ncbi.nlm.nih.gov/pubmed/28503600 http://dx.doi.org/10.1177/2329048X15618970 |
_version_ | 1783233851315716096 |
---|---|
author | Pavlovic, Milen Neubauer, David Al-Tawari, Asma A. |
author_facet | Pavlovic, Milen Neubauer, David Al-Tawari, Asma A. |
author_sort | Pavlovic, Milen |
collection | PubMed |
description | Contamination or transcutaneous absorption of organophosphates (OP) is rare and there exist only few reports of such manner of poisoning. We report four children from the same family in whom temporal proximity of the disease onset, a detailed interrogation of parents and exclusion of other clinical differentials, led to the diagnosis of transcutaneous intoxication with organophosphates (diazinon). The contamination occurred during the game with a freshly used poison can. Uncommon clinical picture was marked by delayed signs predominantly reflecting certain nicotinic effects (muscle weakness, cramps) along with subtle neuropathic features occurring throughout a few weeks after initial event. Our illustrative cases can further contribute to the better awareness and understanding of variable spectrum of transcutaneous route of OP poisoning. |
format | Online Article Text |
id | pubmed-5417017 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-54170172017-05-11 Delayed Effects of Transcutaneous Organophosphate Poisoning in Four Children Pavlovic, Milen Neubauer, David Al-Tawari, Asma A. Child Neurol Open Article Contamination or transcutaneous absorption of organophosphates (OP) is rare and there exist only few reports of such manner of poisoning. We report four children from the same family in whom temporal proximity of the disease onset, a detailed interrogation of parents and exclusion of other clinical differentials, led to the diagnosis of transcutaneous intoxication with organophosphates (diazinon). The contamination occurred during the game with a freshly used poison can. Uncommon clinical picture was marked by delayed signs predominantly reflecting certain nicotinic effects (muscle weakness, cramps) along with subtle neuropathic features occurring throughout a few weeks after initial event. Our illustrative cases can further contribute to the better awareness and understanding of variable spectrum of transcutaneous route of OP poisoning. SAGE Publications 2015-11-27 /pmc/articles/PMC5417017/ /pubmed/28503600 http://dx.doi.org/10.1177/2329048X15618970 Text en © The Author(s) 2015 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Article Pavlovic, Milen Neubauer, David Al-Tawari, Asma A. Delayed Effects of Transcutaneous Organophosphate Poisoning in Four Children |
title | Delayed Effects of Transcutaneous Organophosphate Poisoning in Four Children |
title_full | Delayed Effects of Transcutaneous Organophosphate Poisoning in Four Children |
title_fullStr | Delayed Effects of Transcutaneous Organophosphate Poisoning in Four Children |
title_full_unstemmed | Delayed Effects of Transcutaneous Organophosphate Poisoning in Four Children |
title_short | Delayed Effects of Transcutaneous Organophosphate Poisoning in Four Children |
title_sort | delayed effects of transcutaneous organophosphate poisoning in four children |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417017/ https://www.ncbi.nlm.nih.gov/pubmed/28503600 http://dx.doi.org/10.1177/2329048X15618970 |
work_keys_str_mv | AT pavlovicmilen delayedeffectsoftranscutaneousorganophosphatepoisoninginfourchildren AT neubauerdavid delayedeffectsoftranscutaneousorganophosphatepoisoninginfourchildren AT altawariasmaa delayedeffectsoftranscutaneousorganophosphatepoisoninginfourchildren |