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Decreased Nucleus Accumbens Expression of Psychiatric Disorder Risk Gene Cacna1c Promotes Susceptibility to Social Stress

BACKGROUND: Polymorphisms in the CACNA1C gene are associated with human mood disorders. The rodent social defeat model of stress/mood-disorder susceptibility results in maladaptive consequences mediated by altered function of mesolimbic circuits. METHODS: mRNA levels of Cacna1c in the nucleus accumb...

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Detalles Bibliográficos
Autores principales:	Terrillion, Chantelle E., Francis, T. Chase, Puche, Adam C., Lobo, Mary Kay, Gould, Todd D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417061/ https://www.ncbi.nlm.nih.gov/pubmed/28165117 http://dx.doi.org/10.1093/ijnp/pyw112

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