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The effect of current Schistosoma mansoni infection on the immunogenicity of a candidate TB vaccine, MVA85A, in BCG-vaccinated adolescents: An open-label trial

INTRODUCTION: Helminth infection may affect vaccine immunogenicity and efficacy. Adolescents, a target population for tuberculosis booster vaccines, often have a high helminth burden. We investigated effects of Schistosoma mansoni (Sm) on the immunogenicity and safety of MVA85A, a model candidate tu...

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Detalles Bibliográficos
Autores principales:	Wajja, Anne, Kizito, Dennison, Nassanga, Beatrice, Nalwoga, Angela, Kabagenyi, Joyce, Kimuda, Simon, Galiwango, Ronald, Mutonyi, Gertrude, Vermaak, Samantha, Satti, Iman, Verweij, Jaco, Tukahebwa, Edridah, Cose, Stephen, Levin, Jonathan, Kaleebu, Pontiano, Elliott, Alison M., McShane, Helen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417418/ https://www.ncbi.nlm.nih.gov/pubmed/28472067 http://dx.doi.org/10.1371/journal.pntd.0005440

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