dbOTU3: A new implementation of distribution-based OTU calling

Distribution-based operational taxonomic unit-calling (dbOTU) improves on other approaches by incorporating information about the input sequences’ distribution across samples. Previous implementations of dbOTU presented challenges for users. Here we introduce and evaluate a new implementation of dbO...

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Detalles Bibliográficos
Autores principales: Olesen, Scott W., Duvallet, Claire, Alm, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417438/
https://www.ncbi.nlm.nih.gov/pubmed/28472072
http://dx.doi.org/10.1371/journal.pone.0176335
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author Olesen, Scott W.
Duvallet, Claire
Alm, Eric J.
author_facet Olesen, Scott W.
Duvallet, Claire
Alm, Eric J.
author_sort Olesen, Scott W.
collection PubMed
description Distribution-based operational taxonomic unit-calling (dbOTU) improves on other approaches by incorporating information about the input sequences’ distribution across samples. Previous implementations of dbOTU presented challenges for users. Here we introduce and evaluate a new implementation of dbOTU that is faster and more user-friendly. We show that this new implementation has theoretical and practical improvements over previous implementations of dbOTU, making the algorithm more accessible to microbial ecology and biomedical researchers.
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spelling pubmed-54174382017-05-14 dbOTU3: A new implementation of distribution-based OTU calling Olesen, Scott W. Duvallet, Claire Alm, Eric J. PLoS One Research Article Distribution-based operational taxonomic unit-calling (dbOTU) improves on other approaches by incorporating information about the input sequences’ distribution across samples. Previous implementations of dbOTU presented challenges for users. Here we introduce and evaluate a new implementation of dbOTU that is faster and more user-friendly. We show that this new implementation has theoretical and practical improvements over previous implementations of dbOTU, making the algorithm more accessible to microbial ecology and biomedical researchers. Public Library of Science 2017-05-04 /pmc/articles/PMC5417438/ /pubmed/28472072 http://dx.doi.org/10.1371/journal.pone.0176335 Text en © 2017 Olesen et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Olesen, Scott W.
Duvallet, Claire
Alm, Eric J.
dbOTU3: A new implementation of distribution-based OTU calling
title dbOTU3: A new implementation of distribution-based OTU calling
title_full dbOTU3: A new implementation of distribution-based OTU calling
title_fullStr dbOTU3: A new implementation of distribution-based OTU calling
title_full_unstemmed dbOTU3: A new implementation of distribution-based OTU calling
title_short dbOTU3: A new implementation of distribution-based OTU calling
title_sort dbotu3: a new implementation of distribution-based otu calling
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417438/
https://www.ncbi.nlm.nih.gov/pubmed/28472072
http://dx.doi.org/10.1371/journal.pone.0176335
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