Cargando…

Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus

1-Deoxysphingolipids (1-deoxySLs) are atypical sphingolipids, which are formed in a side reaction during sphingolipid de-novo synthesis. Recently, we demonstrated that 1-deoxySLs are biomarkers for the prediction of T2DM in obese, non-diabetic patients. Here we investigated the relevance of 1-deoxyS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mwinyi, J., Boström, A., Fehrer, I., Othman, A., Waeber, G., Marti-Soler, H., Vollenweider, P., Marques-Vidal, P., Schiöth, H. B., von Eckardstein, A., Hornemann, T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417440/ https://www.ncbi.nlm.nih.gov/pubmed/28472035 http://dx.doi.org/10.1371/journal.pone.0175776

Ejemplares similares

Correction: Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus
por: Mwinyi, J., et al.
Publicado: (2017)

Plasma 1-deoxysphingolipids are predictive biomarkers for type 2 diabetes mellitus
por: Othman, Alaa, et al.
Publicado: (2015)

A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers
por: Xu, Jiayue, et al.
Publicado: (2017)

Salivary cortisol is not associated with incident insulin resistance or type 2 diabetes mellitus
por: Gariani, Karim, et al.
Publicado: (2019)

Deoxysphingoid bases as plasma markers in Diabetes mellitus
por: Bertea, Mariana, et al.
Publicado: (2010)

Metabolic Syndrome, Neurotoxic 1-Deoxysphingolipids and Nervous Tissue Inflammation in Chronic Idiopathic Axonal Polyneuropathy (CIAP)
por: Hube, Larissa, et al.
Publicado: (2017)

1-Deoxysphingolipids, Early Predictors of Type 2 Diabetes, Compromise the Functionality of Skeletal Myoblasts
por: Tran, Duyen, et al.
Publicado: (2021)

Deoxysphingolipids: β-Cell, Beware of These New Kids on the Block
por: Kowluru, Anjaneyulu
Publicado: (2014)

Modulating serine palmitoyltransferase‐deoxysphingolipid axis in cancer therapy
por: Xiang, Yuancai, et al.
Publicado: (2020)

Deoxysphingolipids and ether-linked diacylglycerols accumulate in the tissues of aged mice
por: Ando, Ayumi, et al.
Publicado: (2019)

Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiae
por: Haribowo, A. Galih, et al.
Publicado: (2019)

Imbalanced unfolded protein response signaling contributes to 1-deoxysphingolipid retinal toxicity
por: Rosarda, Jessica D., et al.
Publicado: (2023)

1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an Enigma
por: Duan, Jingjing, et al.
Publicado: (2015)

1-Deoxysphingolipid synthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells
por: Cordes, Thekla, et al.
Publicado: (2022)

Deoxysphingolipids as candidate biomarkers for a novel SPTLC1 mutation associated with HSAN-I
por: Boso, Federica, et al.
Publicado: (2019)

Adipocytokines, Hepatic and Inflammatory Biomarkers and Incidence of Type 2 Diabetes. The CoLaus Study
por: Marques-Vidal, Pedro, et al.
Publicado: (2012)

Epigenomics of Total Acute Sleep Deprivation in Relation to Genome-Wide DNA Methylation Profiles and RNA Expression
por: Nilsson, Emil K., et al.
Publicado: (2016)

Estimating the Risk of Developing Type 2 Diabetes: A Comparison of Several Risk Scores: The Cohorte Lausannoise study
por: Schmid, Rémy, et al.
Publicado: (2011)

Antihypertensive drug treatment changes in the general population: the colaus study
por: Christe, Vanessa, et al.
Publicado: (2014)

Prevalence of measured and reported multimorbidity in a representative sample of the Swiss population
por: Pache, Basile, et al.
Publicado: (2015)

Socio-demographic and lifestyle determinants of dietary patterns in French-speaking Switzerland, 2009–2012
por: Marques-Vidal, Pedro, et al.
Publicado: (2018)

Hyperhomocysteinemia is independently associated with albuminuria in the population-based CoLaus study
por: Marti, Franziska, et al.
Publicado: (2011)

Hepatocyte ABCA1 deficiency is associated with reduced HDL sphingolipids
por: Othman, Alaa, et al.
Publicado: (2023)

A genetic risk score is differentially associated with migraine with and without aura
por: Pisanu, Claudia, et al.
Publicado: (2017)

Circulating microRNAs -192 and -194 are associated with the presence and incidence of diabetes mellitus
por: Jaeger, Andrea, et al.
Publicado: (2018)

SERIneALanine Killer: SPT promiscuity inhibits tumour growth via intra-tumoral deoxysphingolipid production
por: Falcone, Mattia, et al.
Publicado: (2020)

Socio-demographic and behavioural determinants of weight gain in the Swiss population
por: Guerra, Filipa, et al.
Publicado: (2015)

Prevalence and determinants of polypharmacy in Switzerland: data from the CoLaus study
por: Castioni, Julien, et al.
Publicado: (2017)

Polypill eligibility and equivalent intake in a Swiss population-based study
por: Castioni, Julien, et al.
Publicado: (2021)

Impact of smoking on fertility and age of menopause: a population-based assessment
por: Oboni, Jean-Baptiste, et al.
Publicado: (2016)

Hereditary sensory neuropathy type 1-associated deoxysphingolipids cause neurotoxicity, acute calcium handling abnormalities and mitochondrial dysfunction in vitro
por: Wilson, Emma R., et al.
Publicado: (2018)

Altered Distribution of Unesterified Cholesterol among Lipoprotein Subfractions of Patients with Diabetes Mellitus Type 2
por: Kolb, Livia Noemi, et al.
Publicado: (2023)

Prevalence of obesity and abdominal obesity in the Lausanne population
por: Marques-Vidal, Pedro, et al.
Publicado: (2008)

Prevalence and management of cardiovascular risk factors in Portuguese living in Portugal and Portuguese who migrated to Switzerland
por: Alves, Luís, et al.
Publicado: (2015)

Clinical and biological determinants of P-wave duration: cross-sectional data from the population-based CoLaus|PsyCoLaus study
por: Bocchi, Federica, et al.
Publicado: (2020)

Prevalence of atrial fibrillation: The Swiss population-based CoLaus|PsyCoLaus study
por: Samim, Daryoush, et al.
Publicado: (2021)

Longitudinal genome-wide methylation study of Roux-en-Y gastric bypass patients reveals novel CpG sites associated with essential hypertension
por: Boström, Adrian E., et al.
Publicado: (2016)

A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease
por: Schiöth, Helgi B., et al.
Publicado: (2016)

Prevalence and factors associated with difficulty and intention to quit smoking in Switzerland
por: Marques-Vidal, Pedro, et al.
Publicado: (2011)

Low birth weight leads to obesity, diabetes and increased leptin levels in adults: the CoLaus study
por: Jornayvaz, François R., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_n5mev172i9918l70tg5taksv9j