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HBV DNA genome co-transfection procedure for the evaluation of relative fitness

Hepatitis B virus (HBV) has a high mutation rate and exists as a mixture of genetically different but closely related variants. We present a HBV DNA co-transfection fitness assay and use it to evaluate the relative fitness of different HBV variants in two scenarios: seroconversion process and occupa...

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Detalles Bibliográficos
Autores principales: Sevic, Ina, Gonzalez Lopez Ledesma, Maria Mora, Flichman, Diego Martin, Campos, Rodolfo Hector
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417490/
https://www.ncbi.nlm.nih.gov/pubmed/28472081
http://dx.doi.org/10.1371/journal.pone.0175543

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