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Improvement of uridine production of Bacillus subtilis by atmospheric and room temperature plasma mutagenesis and high-throughput screening
In the present study, a novel breeding strategy of atmospheric and room temperature plasma (ARTP) mutagenesis was used to improve the uridine production of engineered Bacillus subtilis TD12np. A high-throughput screening method was established using both resistant plates and 96-well microplates to s...
Autores principales: | Fan, Xiaoguang, Wu, Heyun, Li, Guoliang, Yuan, Hui, Zhang, Hongchao, Li, Yanjun, Xie, Xixian, Chen, Ning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417507/ https://www.ncbi.nlm.nih.gov/pubmed/28472077 http://dx.doi.org/10.1371/journal.pone.0176545 |
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