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Development of prostate specific membrane antigen targeted ultrasound microbubbles using bioorthogonal chemistry
Prostate specific membrane antigen (PSMA) targeted microbubbles (MBs) were developed using bioorthogonal chemistry. Streptavidin-labeled MBs were treated with a biotinylated tetrazine (MB(Tz)) and targeted to PSMA expressing cells using trans-cyclooctene (TCO)-functionalized anti-PSMA antibodies (TC...
Autores principales: | Zlitni, Aimen, Yin, Melissa, Janzen, Nancy, Chatterjee, Samit, Lisok, Ala, Gabrielson, Kathleen L., Nimmagadda, Sridhar, Pomper, Martin G., Foster, F. Stuart, Valliant, John F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417523/ https://www.ncbi.nlm.nih.gov/pubmed/28472168 http://dx.doi.org/10.1371/journal.pone.0176958 |
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