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Comparative analysis of the sensitivity of metagenomic sequencing and PCR to detect a biowarfare simulant (Bacillus atrophaeus) in soil samples

To evaluate the sensitivity of high-throughput DNA sequencing for monitoring biowarfare agents in the environment, we analysed soil samples inoculated with different amounts of Bacillus atrophaeus, a surrogate organism for Bacillus anthracis. The soil samples considered were a poorly carbonated soil...

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Detalles Bibliográficos
Autores principales: Plaire, Delphine, Puaud, Simon, Marsolier-Kergoat, Marie-Claude, Elalouf, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417559/
https://www.ncbi.nlm.nih.gov/pubmed/28472119
http://dx.doi.org/10.1371/journal.pone.0177112