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Mammalian Target of Rapamycin (mTOR) Regulates Transforming Growth Factor-β(1) (TGF-β(1))-Induced Epithelial-Mesenchymal Transition via Decreased Pyruvate Kinase M2 (PKM2) Expression in Cervical Cancer Cells
BACKGROUND: Epithelial-mesenchymal transition (EMT) plays an important role in cancer tumorigenesis. Transforming growth factor β(1) (TGF-β(1)) can induced EMT, which could increase tumor migration and invasion. Moreover, recent studies have been proven that mammalian target of rapamycin (mTOR) is a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417590/ https://www.ncbi.nlm.nih.gov/pubmed/28446743 http://dx.doi.org/10.12659/MSM.901542 |