Induction of endogenous retroelements as a potential mechanism for mouse-specific drug-induced carcinogenicity

A number of chemical compounds have been shown to induce liver tumors in mice but not in other species. While several mechanisms for this species-specific tumorigenicity have been proposed, no definitive mechanism has been established. We examined the effects of the nongenotoxic rodent hepatic carci...

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Detalles Bibliográficos
Autores principales: Coskran, Timothy M., Jiang, Zhijie, Klaunig, James E., Mager, Dixie L., Obert, Leslie, Robertson, Andrew, Tsinoremas, Nicholas, Wang, Zemin, Gosink, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417610/
https://www.ncbi.nlm.nih.gov/pubmed/28472135
http://dx.doi.org/10.1371/journal.pone.0176768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417610/
https://www.ncbi.nlm.nih.gov/pubmed/28472135
http://dx.doi.org/10.1371/journal.pone.0176768

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