Epithelial-to-mesenchymal transition correlates with gefitinib resistance in NSCLC cells and the liver X receptor ligand GW3965 reverses gefitinib resistance through inhibition of vimentin

The role of epithelial-to-mesenchymal transition in cancer drug resistance is increasingly acknowledged. We examined whether epithelial-to-mesenchymal transition affects gefitinib resistance in non-small cell lung cancer (NSCLC) cells. Cell viability was detected by CCK-8 assay, VIM expression level...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Yong, Zang, Jialan, Qin, Xiaobing, Yan, Dali, Cao, Haixia, Zhou, Leilei, Ni, Jie, Yu, Shaorong, Wu, Jianzhong, Feng, Ji-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417672/
https://www.ncbi.nlm.nih.gov/pubmed/28496332
http://dx.doi.org/10.2147/OTT.S124757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417672/
https://www.ncbi.nlm.nih.gov/pubmed/28496332
http://dx.doi.org/10.2147/OTT.S124757

Ejemplares similares