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Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma

Ovarian cancer, a leading cause of death in women, typically spreads locally and rarely metastasizes to the brain or seeds the leptomeninges. We present a case of a 62-year-old woman with a history of treated ovarian cell carcinoma who developed bilateral sensorineural deafness and right-sided facia...

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Autores principales: Krupa, Martin, Byun, Kathy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417755/
https://www.ncbi.nlm.nih.gov/pubmed/28491194
http://dx.doi.org/10.1016/j.radcr.2017.03.013
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author Krupa, Martin
Byun, Kathy
author_facet Krupa, Martin
Byun, Kathy
author_sort Krupa, Martin
collection PubMed
description Ovarian cancer, a leading cause of death in women, typically spreads locally and rarely metastasizes to the brain or seeds the leptomeninges. We present a case of a 62-year-old woman with a history of treated ovarian cell carcinoma who developed bilateral sensorineural deafness and right-sided facial weakness and on imaging was found to have bilateral internal auditory canal (IAC) masses and leptomeningeal carcinomatosis, pathologically proven by cerebrospinal fluid cytology. We discuss her magnetic resonance imaging and positron emission tomography-computed tomography findings and review the imaging characteristics of IAC metastases. Finally, we review the literature on leptomeningeal carcinomatosis from ovarian cancer and discuss the high incidence of bilateral IAC metastases in patients with leptomeningeal carcinomatosis.
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spelling pubmed-54177552017-05-10 Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma Krupa, Martin Byun, Kathy Radiol Case Rep Case Report Ovarian cancer, a leading cause of death in women, typically spreads locally and rarely metastasizes to the brain or seeds the leptomeninges. We present a case of a 62-year-old woman with a history of treated ovarian cell carcinoma who developed bilateral sensorineural deafness and right-sided facial weakness and on imaging was found to have bilateral internal auditory canal (IAC) masses and leptomeningeal carcinomatosis, pathologically proven by cerebrospinal fluid cytology. We discuss her magnetic resonance imaging and positron emission tomography-computed tomography findings and review the imaging characteristics of IAC metastases. Finally, we review the literature on leptomeningeal carcinomatosis from ovarian cancer and discuss the high incidence of bilateral IAC metastases in patients with leptomeningeal carcinomatosis. Elsevier 2017-04-05 /pmc/articles/PMC5417755/ /pubmed/28491194 http://dx.doi.org/10.1016/j.radcr.2017.03.013 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Krupa, Martin
Byun, Kathy
Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma
title Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma
title_full Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma
title_fullStr Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma
title_full_unstemmed Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma
title_short Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma
title_sort leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417755/
https://www.ncbi.nlm.nih.gov/pubmed/28491194
http://dx.doi.org/10.1016/j.radcr.2017.03.013
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