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Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma
Ovarian cancer, a leading cause of death in women, typically spreads locally and rarely metastasizes to the brain or seeds the leptomeninges. We present a case of a 62-year-old woman with a history of treated ovarian cell carcinoma who developed bilateral sensorineural deafness and right-sided facia...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417755/ https://www.ncbi.nlm.nih.gov/pubmed/28491194 http://dx.doi.org/10.1016/j.radcr.2017.03.013 |
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author | Krupa, Martin Byun, Kathy |
author_facet | Krupa, Martin Byun, Kathy |
author_sort | Krupa, Martin |
collection | PubMed |
description | Ovarian cancer, a leading cause of death in women, typically spreads locally and rarely metastasizes to the brain or seeds the leptomeninges. We present a case of a 62-year-old woman with a history of treated ovarian cell carcinoma who developed bilateral sensorineural deafness and right-sided facial weakness and on imaging was found to have bilateral internal auditory canal (IAC) masses and leptomeningeal carcinomatosis, pathologically proven by cerebrospinal fluid cytology. We discuss her magnetic resonance imaging and positron emission tomography-computed tomography findings and review the imaging characteristics of IAC metastases. Finally, we review the literature on leptomeningeal carcinomatosis from ovarian cancer and discuss the high incidence of bilateral IAC metastases in patients with leptomeningeal carcinomatosis. |
format | Online Article Text |
id | pubmed-5417755 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-54177552017-05-10 Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma Krupa, Martin Byun, Kathy Radiol Case Rep Case Report Ovarian cancer, a leading cause of death in women, typically spreads locally and rarely metastasizes to the brain or seeds the leptomeninges. We present a case of a 62-year-old woman with a history of treated ovarian cell carcinoma who developed bilateral sensorineural deafness and right-sided facial weakness and on imaging was found to have bilateral internal auditory canal (IAC) masses and leptomeningeal carcinomatosis, pathologically proven by cerebrospinal fluid cytology. We discuss her magnetic resonance imaging and positron emission tomography-computed tomography findings and review the imaging characteristics of IAC metastases. Finally, we review the literature on leptomeningeal carcinomatosis from ovarian cancer and discuss the high incidence of bilateral IAC metastases in patients with leptomeningeal carcinomatosis. Elsevier 2017-04-05 /pmc/articles/PMC5417755/ /pubmed/28491194 http://dx.doi.org/10.1016/j.radcr.2017.03.013 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Krupa, Martin Byun, Kathy Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma |
title | Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma |
title_full | Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma |
title_fullStr | Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma |
title_full_unstemmed | Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma |
title_short | Leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma |
title_sort | leptomeningeal carcinomatosis and bilateral internal auditory canal metastases from ovarian carcinoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417755/ https://www.ncbi.nlm.nih.gov/pubmed/28491194 http://dx.doi.org/10.1016/j.radcr.2017.03.013 |
work_keys_str_mv | AT krupamartin leptomeningealcarcinomatosisandbilateralinternalauditorycanalmetastasesfromovariancarcinoma AT byunkathy leptomeningealcarcinomatosisandbilateralinternalauditorycanalmetastasesfromovariancarcinoma |