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Covariation of Peptide Abundances Accurately Reflects Protein Concentration Differences

Most implementations of mass spectrometry-based proteomics involve enzymatic digestion of proteins, expanding the analysis to multiple proteolytic peptides for each protein. Currently, there is no consensus of how to summarize peptides' abundances to protein concentrations, and such efforts are...

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Detalles Bibliográficos
Autores principales:	Zhang, Bo, Pirmoradian, Mohammad, Zubarev, Roman, Käll, Lukas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2017
Materias:	Technological Innovation and Resources
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417831/ https://www.ncbi.nlm.nih.gov/pubmed/28302922 http://dx.doi.org/10.1074/mcp.O117.067728

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