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Radiovaccination Hypothesis
The details of patients who have entered remission from metastatic melanoma following palliative radiotherapy are reported. We review the relevant immune physiology and radiotherapy particulars and propose the hypothesis that radiovaccination with high fractional dose to skin metastases can stimulat...
| Autor principal: | |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cureus
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418027/ https://www.ncbi.nlm.nih.gov/pubmed/28480153 http://dx.doi.org/10.7759/cureus.1135 |
| _version_ | 1783234007311319040 |
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| author | Eapen, Libni |
| author_facet | Eapen, Libni |
| author_sort | Eapen, Libni |
| collection | PubMed |
| description | The details of patients who have entered remission from metastatic melanoma following palliative radiotherapy are reported. We review the relevant immune physiology and radiotherapy particulars and propose the hypothesis that radiovaccination with high fractional dose to skin metastases can stimulate the development of a robust systemic anti-tumoral immune response capable of causing remission of metastatic disease. |
| format | Online Article Text |
| id | pubmed-5418027 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | Cureus |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-54180272017-05-05 Radiovaccination Hypothesis Eapen, Libni Cureus Oncology The details of patients who have entered remission from metastatic melanoma following palliative radiotherapy are reported. We review the relevant immune physiology and radiotherapy particulars and propose the hypothesis that radiovaccination with high fractional dose to skin metastases can stimulate the development of a robust systemic anti-tumoral immune response capable of causing remission of metastatic disease. Cureus 2017-04-04 /pmc/articles/PMC5418027/ /pubmed/28480153 http://dx.doi.org/10.7759/cureus.1135 Text en Copyright © 2017, Eapen et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| spellingShingle | Oncology Eapen, Libni Radiovaccination Hypothesis |
| title | Radiovaccination Hypothesis |
| title_full | Radiovaccination Hypothesis |
| title_fullStr | Radiovaccination Hypothesis |
| title_full_unstemmed | Radiovaccination Hypothesis |
| title_short | Radiovaccination Hypothesis |
| title_sort | radiovaccination hypothesis |
| topic | Oncology |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418027/ https://www.ncbi.nlm.nih.gov/pubmed/28480153 http://dx.doi.org/10.7759/cureus.1135 |
| work_keys_str_mv | AT eapenlibni radiovaccinationhypothesis |