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The histone demethylase KDM4B regulates peritoneal seeding of ovarian cancer

Epithelial ovarian cancer (EOC) has poor prognosis and rapid recurrence because of widespread dissemination of peritoneal metastases at diagnosis. Multiple pathways contribute to the aggressiveness of ovarian cancer, including hypoxic signaling mechanisms. In this study, we have determined that the...

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Detalles Bibliográficos
Autores principales: Wilson, C, Qiu, L, Hong, Y, Karnik, T, Tadros, G, Mau, B, Ma, T, Mu, Y, New, J, Louie, R J, Gunewardena, S, Godwin, A K, Tawfik, O W, Chien, J, Roby, K F, Krieg, A J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418103/
https://www.ncbi.nlm.nih.gov/pubmed/27869162
http://dx.doi.org/10.1038/onc.2016.412