Insulin‐like growth factor 1 deficiency exacerbates hypertension‐induced cerebral microhemorrhages in mice, mimicking the aging phenotype

Clinical and experimental studies show that aging exacerbates hypertension‐induced cerebral microhemorrhages (CMHs), which progressively impair neuronal function. There is growing evidence that aging promotes insulin‐like growth factor 1 (IGF‐1) deficiency, which compromises multiple aspects of cere...

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Detalles Bibliográficos
Autores principales: Tarantini, Stefano, Valcarcel‐Ares, Noa M., Yabluchanskiy, Andriy, Springo, Zsolt, Fulop, Gabor A., Ashpole, Nicole, Gautam, Tripti, Giles, Cory B., Wren, Jonathan D., Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418199/
https://www.ncbi.nlm.nih.gov/pubmed/28295976
http://dx.doi.org/10.1111/acel.12583

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