Expansion of myeloid‐derived suppressor cells with aging in the bone marrow of mice through a NF‐κB‐dependent mechanism

With aging, there is progressive loss of tissue homeostasis and functional reserve, leading to an impaired response to stress and an increased risk of morbidity and mortality. A key mediator of the cellular response to damage and stress is the transcription factor NF‐κB. We demonstrated previously t...

Descripción completa

Detalles Bibliográficos
Autores principales: Flores, Rafael R., Clauson, Cheryl L., Cho, Joonseok, Lee, Byeong‐Chel, McGowan, Sara J., Baker, Darren J., Niedernhofer, Laura J., Robbins, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418207/
https://www.ncbi.nlm.nih.gov/pubmed/28229533
http://dx.doi.org/10.1111/acel.12571

Ejemplares similares

Ejemplares similares