Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson‐Gilford progeria syndrome

Hutchinson‐Gilford progeria syndrome (HGPS) constitutes a genetic disease wherein an aging phenotype manifests in childhood. Recent studies indicate that reactive oxygen species (ROS) play important roles in HGPS phenotype progression. Thus, pharmacological reduction in ROS levels has been proposed...

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Detalles Bibliográficos
Autores principales: Kang, Hyun Tae, Park, Joon Tae, Choi, Kobong, Choi, Hyo Jei Claudia, Jung, Chul Won, Kim, Gyu Ree, Lee, Young‐Sam, Park, Sang Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418208/
https://www.ncbi.nlm.nih.gov/pubmed/28317242
http://dx.doi.org/10.1111/acel.12584

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