Fragile X-Associated Tremor/Ataxia Syndrome: From Molecular Pathogenesis to Development of Therapeutics

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder caused by a premutation CGG repeat expansion (55–200 repeats) within the 5′ UTR of the fragile X gene (FMR1). FXTAS is characterized by intension tremor, cerebellar ataxia, progressive neurodegeneration, parkinsonism...

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Detalles Bibliográficos
Autores principales: Kong, Ha Eun, Zhao, Juan, Xu, Shunliang, Jin, Peng, Jin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418347/
https://www.ncbi.nlm.nih.gov/pubmed/28529475
http://dx.doi.org/10.3389/fncel.2017.00128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418347/
https://www.ncbi.nlm.nih.gov/pubmed/28529475
http://dx.doi.org/10.3389/fncel.2017.00128

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