Cargando…

MiR-30b Attenuates Neuropathic Pain by Regulating Voltage-Gated Sodium Channel Nav1.3 in Rats

Nav1.3 is a tetrodotoxin-sensitive isoform among voltage-gated sodium channels that are closely associated with neuropathic pain. It can be up-regulated following nerve injury, but its biological function remains uncertain. MicroRNAs (miRNAs) are endogenous non-coding RNAs that can regulate post-tra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Songxue, Shao, Jinping, Zhao, Qingzan, Ren, Xiuhua, Cai, Weihua, Li, Lei, Bai, Qian, Chen, Xuemei, Xu, Bo, Wang, Jian, Cao, Jing, Zang, Weidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418349/ https://www.ncbi.nlm.nih.gov/pubmed/28529474 http://dx.doi.org/10.3389/fnmol.2017.00126

Ejemplares similares

MicroRNA-30b regulates expression of the sodium channel Nav1.7 in nerve injury-induced neuropathic pain in the rat
por: Shao, Jinping, et al.
Publicado: (2016)

MicroRNA-182 Alleviates Neuropathic Pain by Regulating Nav1.7 Following Spared Nerve Injury in Rats
por: Cai, Weihua, et al.
Publicado: (2018)

Effects of acidosis on neuronal voltage-gated sodium channels: Nav1.1 and Nav1.3
por: Ghovanloo, Mohammad-Reza, et al.
Publicado: (2018)

Na(+)/Ca(2+) selectivity in the bacterial voltage-gated sodium channel NavAb
por: Corry, Ben
Publicado: (2013)

Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics
por: Dvorak, Nolan M., et al.
Publicado: (2020)

The Functional Role of Voltage-Gated Sodium Channel Nav1.5 in Metastatic Breast Cancer
por: Luo, Qianxuan, et al.
Publicado: (2020)

Role of the voltage-gated sodium channel Nav1.6 in glioma and candidate drugs screening
por: Ai, Yong, et al.
Publicado: (2023)

Phosphorylation of a chronic pain mutation in the voltage-gated sodium channel Nav1.7 increases voltage sensitivity
por: Kerth, Clara M., et al.
Publicado: (2020)

Voltage sensor dynamics of a bacterial voltage-gated sodium channel NavAb reveal three conformational states
por: Han, Shuo, et al.
Publicado: (2023)

shRNA mediated knockdown of Nav1.7 in rat dorsal root ganglion attenuates pain following burn injury
por: Cai, Weihua, et al.
Publicado: (2016)

Are voltage-gated sodium channels on the dorsal root ganglion involved in the development of neuropathic pain?
por: Wang, Wei, et al.
Publicado: (2011)

Elevated Neuronal Excitability Due to Modulation of the Voltage-Gated Sodium Channel Nav1.6 by Aβ(1−42)
por: Wang, Xi, et al.
Publicado: (2016)

Thermal melt circular dichroism spectroscopic studies for identifying stabilising amphipathic molecules for the voltage‐gated sodium channel NavMs
por: Ireland, Sam M., et al.
Publicado: (2017)

Fenestropathy of Voltage-Gated Sodium Channels
por: Gamal El-Din, Tamer M., et al.
Publicado: (2022)

Voltage-gated sodium channels assemble and gate as dimers
por: Clatot, Jérôme, et al.
Publicado: (2017)

Correlation of Nav1.8 and Nav1.9 sodium channel expression with neuropathic pain in human subjects with lingual nerve neuromas
por: Bird, Emma V, et al.
Publicado: (2013)

Excitability Constraints on Voltage-Gated Sodium Channels
por: Angelino, Elaine, et al.
Publicado: (2007)

Neurological perspectives on voltage-gated sodium channels
por: Eijkelkamp, Niels, et al.
Publicado: (2012)

Overview of the voltage-gated sodium channel family
por: Yu, Frank H, et al.
Publicado: (2003)

Voltage-gated sodium channels in the mammalian heart
por: Zimmer, Thomas, et al.
Publicado: (2014)

Cannabidiol interactions with voltage-gated sodium channels
por: Sait, Lily Goodyer, et al.
Publicado: (2020)

Calmodulin Interactions with Voltage-Gated Sodium Channels
por: Wu, Xin, et al.
Publicado: (2021)

Structural Advances in Voltage-Gated Sodium Channels
por: Jiang, Daohua, et al.
Publicado: (2022)

Phosphoinositide regulation of voltage-gated sodium channels
por: Short, Ben
Publicado: (2023)

Distribution of Voltage-Gated Sodium Channel (Nav) Alleles among the Aedes aegypti Populations In Central Java Province and Its Association with Resistance to Pyrethroid Insecticides
por: Sayono, Sayono, et al.
Publicado: (2016)

Goshajinkigan, a Traditional Japanese Medicine, Suppresses Voltage-Gated Sodium Channel Nav1.4 Currents in C2C12 Cells
por: Imai, Ryota, et al.
Publicado: (2020)

Recent Developments Regarding Voltage-Gated Sodium Channel Blockers for the Treatment of Inherited and Acquired Neuropathic Pain Syndromes
por: Theile, Jonathan W., et al.
Publicado: (2011)

Dehydrocrenatidine Inhibits Voltage-Gated Sodium Channels and Ameliorates Mechanic Allodia in a Rat Model of Neuropathic Pain
por: Zhao, Fang, et al.
Publicado: (2019)

The Sigma-1 Receptor Binds to the Nav1.5 Voltage-gated Na(+) Channel with 4-Fold Symmetry
por: Balasuriya, Dilshan, et al.
Publicado: (2012)

Voltage-gated sodium channels in taste bud cells
por: Gao, Na, et al.
Publicado: (2009)

THE CRYSTAL STRUCTURE OF A VOLTAGE-GATED SODIUM CHANNEL
por: Payandeh, Jian, et al.
Publicado: (2011)

Neurotoxins and Their Binding Areas on Voltage-Gated Sodium Channels
por: Stevens, Marijke, et al.
Publicado: (2011)

Screening for Voltage-Gated Sodium Channel Interacting Peptides
por: Meng, Er, et al.
Publicado: (2014)

Shellfish Toxins Targeting Voltage-Gated Sodium Channels
por: Zhang, Fan, et al.
Publicado: (2013)

Action of Clathrodin and Analogues on Voltage-Gated Sodium Channels
por: Peigneur, Steve, et al.
Publicado: (2014)

Marine Toxins That Target Voltage-gated Sodium Channels
por: Al-Sabi, Ahmed, et al.
Publicado: (2006)

Theoretical and simulation studies on voltage-gated sodium channels
por: Li, Yang, et al.
Publicado: (2015)

The hitchhiker’s guide to the voltage-gated sodium channel galaxy
por: Ahern, Christopher A., et al.
Publicado: (2016)

Voltage gated sodium channels as drug discovery targets
por: Bagal, Sharan K, et al.
Publicado: (2015)

Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres
por: Carbonara, Roberta, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_bdm8q94mbbu36m3p55vf9ipuq9