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LDL cholesterol counteracts the antitumour effect of tyrosine kinase inhibitors against renal cell carcinoma

BACKGROUND: Treatment with tyrosine kinase inhibitors (TKIs) significantly improves survival of patients with renal cell carcinoma (RCC). However, about one-quarter of the RCC patients are primarily refractory to treatment with TKIs. METHODS: We examined viability of RCC and endothelial cells treate...

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Detalles Bibliográficos
Autores principales:	Naito, Sei, Makhov, Peter, Astsaturov, Igor, Golovine, Konstantin, Tulin, Alexei, Kutikov, Alexander, Uzzo, Robert G, Kolenko, Vladimir M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418451/ https://www.ncbi.nlm.nih.gov/pubmed/28350788 http://dx.doi.org/10.1038/bjc.2017.77

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