Facile access to potent antiviral quinazoline heterocycles with fluorescence properties via merging metal-free domino reactions

Most of the known approved drugs comprise functionalized heterocyclic compounds as subunits. Among them, non-fluorescent quinazolines with four different substitution patterns are found in a variety of clinically used pharmaceuticals, while 4,5,7,8-substituted quinazolines and those displaying their...

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Detalles Bibliográficos
Autores principales: Held, Felix E., Guryev, Anton A., Fröhlich, Tony, Hampel, Frank, Kahnt, Axel, Hutterer, Corina, Steingruber, Mirjam, Bahsi, Hanife, von Bojničić-Kninski, Clemens, Mattes, Daniela S., Foertsch, Tobias C., Nesterov-Mueller, Alexander, Marschall, Manfred, Tsogoeva, Svetlana B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418574/
https://www.ncbi.nlm.nih.gov/pubmed/28462939
http://dx.doi.org/10.1038/ncomms15071

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