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Biosynthesis of the antibiotic nonribosomal peptide penicillin in baker's yeast

Fungi are a valuable source of enzymatic diversity and therapeutic natural products including antibiotics. Here we engineer the baker's yeast Saccharomyces cerevisiae to produce and secrete the antibiotic penicillin, a beta-lactam nonribosomal peptide, by taking genes from a filamentous fungus...

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Detalles Bibliográficos
Autores principales:	Awan, Ali R., Blount, Benjamin A., Bell, David J., Shaw, William M., Ho, Jack C.H., McKiernan, Robert M., Ellis, Tom
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418595/ https://www.ncbi.nlm.nih.gov/pubmed/28469278 http://dx.doi.org/10.1038/ncomms15202

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