Genetic variation and RNA structure regulate microRNA biogenesis

MiRNA biogenesis is highly regulated at the post-transcriptional level; however, the role of sequence and secondary RNA structure in this process has not been extensively studied. A single G to A substitution present in the terminal loop of pri-mir-30c-1 in breast and gastric cancer patients had bee...

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Detalles Bibliográficos
Autores principales: Fernandez, Noemi, Cordiner, Ross A., Young, Robert S., Hug, Nele, Macias, Sara, Cáceres, Javier F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418625/
https://www.ncbi.nlm.nih.gov/pubmed/28466845
http://dx.doi.org/10.1038/ncomms15114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418625/
https://www.ncbi.nlm.nih.gov/pubmed/28466845
http://dx.doi.org/10.1038/ncomms15114

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