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In vivo imaging of leucine aminopeptidase activity in drug-induced liver injury and liver cancer via a near-infrared fluorescent probe

The liver, a main detoxification organ, has evolved a complex enzymatic system to respond to multiple pathological conditions, in which leucine aminopeptidase (LAP) has been reported to participate in detoxifying cisplatin in hepatoma cells and contribute to the intrinsic drug resistance. In vivo im...

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Detalles Bibliográficos
Autores principales:	He, Xinyuan, Li, Lihong, Fang, Yu, Shi, Wen, Li, Xiaohua, Ma, Huimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418645/ https://www.ncbi.nlm.nih.gov/pubmed/28507720 http://dx.doi.org/10.1039/c6sc05712h

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