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Molecular mechanism of cardol, isolated from Trigona incisa stingless bee propolis, induced apoptosis in the SW620 human colorectal cancer cell line
BACKGROUND: Cardol is a major bioactive constituent in the Trigona incisa propolis from Indonesia, with a strong in vitro antiproliferative activity against the SW620 colorectal adenocarcinoma cell line (IC(50) of 4.51 ± 0.76 μg/mL). Cardol induced G(0)/G(1) cell cycle arrest and apoptotic cell deat...
Autores principales: | Kustiawan, Paula Mariana, Lirdprapamongkol, Kriengsak, Palaga, Tanapat, Puthong, Songchan, Phuwapraisirisan, Preecha, Svasti, Jisnuson, Chanchao, Chanpen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418687/ https://www.ncbi.nlm.nih.gov/pubmed/28472978 http://dx.doi.org/10.1186/s40360-017-0139-4 |
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