Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages

BACKGROUND: Solid tumors residing in tissues and organs leave footprints in circulation through circulating tumor cells (CTCs) and circulating tumor DNAs (ctDNA). Characterization of the ctDNA portraits and comparison with tumor DNA mutational portraits may reveal clinically actionable information o...

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Detalles Bibliográficos
Autores principales: Yang, Meng, Topaloglu, Umit, Petty, W. Jeffrey, Pagni, Matthew, Foley, Kristie L., Grant, Stefan C., Robinson, Mac, Bitting, Rhonda L., Thomas, Alexandra, Alistar, Angela T., Desnoyers, Rodwige J., Goodman, Michael, Albright, Carol, Porosnicu, Mercedes, Vatca, Mihaela, Qasem, Shadi A., DeYoung, Barry, Kytola, Ville, Nykter, Matti, Chen, Kexin, Levine, Edward A., Staren, Edgar D., D’Agostino, Ralph B., Petro, Robin M., Blackstock, William, Powell, Bayard L., Abraham, Edward, Pasche, Boris, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418716/
https://www.ncbi.nlm.nih.gov/pubmed/28472989
http://dx.doi.org/10.1186/s13045-017-0468-1

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