Paternal age effects on sperm FOXK1 and KCNA7 methylation and transmission into the next generation

Children of older fathers carry an increased risk for developing autism and other disorders. To elucidate the underlying mechanisms, we investigated the correlation of sperm DNA methylation with paternal age and its impact on the epigenome of the offspring. Methylation levels of nine candidate genes...

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Detalles Bibliográficos
Autores principales: Atsem, Stefanie, Reichenbach, Juliane, Potabattula, Ramya, Dittrich, Marcus, Nava, Caroline, Depienne, Christel, Böhm, Lena, Rost, Simone, Hahn, Thomas, Schorsch, Martin, Haaf, Thomas, El Hajj, Nady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418740/
https://www.ncbi.nlm.nih.gov/pubmed/28171595
http://dx.doi.org/10.1093/hmg/ddw328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418740/
https://www.ncbi.nlm.nih.gov/pubmed/28171595
http://dx.doi.org/10.1093/hmg/ddw328

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