Cargando…
Paternal age effects on sperm FOXK1 and KCNA7 methylation and transmission into the next generation
Children of older fathers carry an increased risk for developing autism and other disorders. To elucidate the underlying mechanisms, we investigated the correlation of sperm DNA methylation with paternal age and its impact on the epigenome of the offspring. Methylation levels of nine candidate genes...
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418740/ https://www.ncbi.nlm.nih.gov/pubmed/28171595 http://dx.doi.org/10.1093/hmg/ddw328 |