High levels of sarcospan are well tolerated and act as a sarcolemmal stabilizer to address skeletal muscle and pulmonary dysfunction in DMD

Duchenne muscular dystrophy (DMD) is a genetic disorder that causes progressive muscle weakness, ultimately leading to early mortality in affected teenagers and young adults. Previous work from our lab has shown that a small transmembrane protein called sarcospan (SSPN) can enhance the recruitment o...

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Detalles Bibliográficos
Autores principales: Gibbs, Elizabeth M., Marshall, Jamie L., Ma, Eva, Nguyen, Thien M., Hong, Grace, Lam, Jessica S., Spencer, Melissa J., Crosbie-Watson, Rachelle H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418831/
https://www.ncbi.nlm.nih.gov/pubmed/27798107
http://dx.doi.org/10.1093/hmg/ddw356

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