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Age differences in diabetes-related complications and glycemic control

BACKGROUND: This study aimed to examine the associations of age with the presence of complications and glycemic control in the Northwest of Iran. METHODS: A total of 649 people with diabetes who were >25 years old and had a caring record in diabetes clinics in two Northwestern provinces of Iran d...

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Autores principales: Shamshirgaran, S. M., Mamaghanian, A., Aliasgarzadeh, A., Aiminisani, N., Iranparvar-Alamdari, M., Ataie, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418847/
https://www.ncbi.nlm.nih.gov/pubmed/28472985
http://dx.doi.org/10.1186/s12902-017-0175-5
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author Shamshirgaran, S. M.
Mamaghanian, A.
Aliasgarzadeh, A.
Aiminisani, N.
Iranparvar-Alamdari, M.
Ataie, J.
author_facet Shamshirgaran, S. M.
Mamaghanian, A.
Aliasgarzadeh, A.
Aiminisani, N.
Iranparvar-Alamdari, M.
Ataie, J.
author_sort Shamshirgaran, S. M.
collection PubMed
description BACKGROUND: This study aimed to examine the associations of age with the presence of complications and glycemic control in the Northwest of Iran. METHODS: A total of 649 people with diabetes who were >25 years old and had a caring record in diabetes clinics in two Northwestern provinces of Iran during 2014–15, were recruited in this cross-sectional study. General information including demographic, socioeconomic status and lifestyle factors were collected by trained interviewers. Clinical information was retrieved from clinic's record. Univariate and multivariate logistic regression were performed to assess the predictors of diabetes outcome of interest as well as to clarify the role of age in relation to these outcomes. RESULTS: Compared to the age group of ≤49, the middle age group (50–59) and the older age group (60 years of age and older) were less likely to report poor glycemic control (OR fully adjusted = 0.49 95% CI: 0.28–0.86 and (OR = 0.44 95% CI: 0.24–0.80), respectively. Additionally, poor glycemic control was associated with income level, disease duration, hypercholesterolemia, high level of LDL and hypertension. In contrast, age was associated with the highest percentage of complications. People with duration of >7 years of disease record were 6 times more likely to have complications (OR(adj) = 5.98 95% CI: 2.35–15.22). CONCLUSION: Although the prevalence of complications was higher among the older diabetic patients, they had a better glycemic control. The influential factors were variably associated with the two diabetes-related outcomes; therefore, a more comprehensive risk profiles assessment is needed for glycemic control. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12902-017-0175-5) contains supplementary material, which is available to authorized users.
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spelling pubmed-54188472017-05-08 Age differences in diabetes-related complications and glycemic control Shamshirgaran, S. M. Mamaghanian, A. Aliasgarzadeh, A. Aiminisani, N. Iranparvar-Alamdari, M. Ataie, J. BMC Endocr Disord Research Article BACKGROUND: This study aimed to examine the associations of age with the presence of complications and glycemic control in the Northwest of Iran. METHODS: A total of 649 people with diabetes who were >25 years old and had a caring record in diabetes clinics in two Northwestern provinces of Iran during 2014–15, were recruited in this cross-sectional study. General information including demographic, socioeconomic status and lifestyle factors were collected by trained interviewers. Clinical information was retrieved from clinic's record. Univariate and multivariate logistic regression were performed to assess the predictors of diabetes outcome of interest as well as to clarify the role of age in relation to these outcomes. RESULTS: Compared to the age group of ≤49, the middle age group (50–59) and the older age group (60 years of age and older) were less likely to report poor glycemic control (OR fully adjusted = 0.49 95% CI: 0.28–0.86 and (OR = 0.44 95% CI: 0.24–0.80), respectively. Additionally, poor glycemic control was associated with income level, disease duration, hypercholesterolemia, high level of LDL and hypertension. In contrast, age was associated with the highest percentage of complications. People with duration of >7 years of disease record were 6 times more likely to have complications (OR(adj) = 5.98 95% CI: 2.35–15.22). CONCLUSION: Although the prevalence of complications was higher among the older diabetic patients, they had a better glycemic control. The influential factors were variably associated with the two diabetes-related outcomes; therefore, a more comprehensive risk profiles assessment is needed for glycemic control. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12902-017-0175-5) contains supplementary material, which is available to authorized users. BioMed Central 2017-05-04 /pmc/articles/PMC5418847/ /pubmed/28472985 http://dx.doi.org/10.1186/s12902-017-0175-5 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Shamshirgaran, S. M.
Mamaghanian, A.
Aliasgarzadeh, A.
Aiminisani, N.
Iranparvar-Alamdari, M.
Ataie, J.
Age differences in diabetes-related complications and glycemic control
title Age differences in diabetes-related complications and glycemic control
title_full Age differences in diabetes-related complications and glycemic control
title_fullStr Age differences in diabetes-related complications and glycemic control
title_full_unstemmed Age differences in diabetes-related complications and glycemic control
title_short Age differences in diabetes-related complications and glycemic control
title_sort age differences in diabetes-related complications and glycemic control
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418847/
https://www.ncbi.nlm.nih.gov/pubmed/28472985
http://dx.doi.org/10.1186/s12902-017-0175-5
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