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Downregulating ANP32A rescues synapse and memory loss via chromatin remodeling in Alzheimer model

BACKGROUND: The impairment of histone acetylation is causally linked to the cognitive decline in Alzheimer’s disease (AD). In addition to histone acetyltransferases (HATs) and histone deacetylases (HDACs), inhibitor of acetyltransferases (INHAT) can also regulate histone acetylation. As a key compon...

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Detalles Bibliográficos
Autores principales:	Chai, Gao-Shang, Feng, Qiong, Wang, Zhi-Hao, Hu, Yu, Sun, Dong-Sheng, Li, Xiao-Guang, Ke, Dan, Li, Hong-Lian, Liu, Gong-Ping, Wang, Jian-Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418850/ https://www.ncbi.nlm.nih.gov/pubmed/28472990 http://dx.doi.org/10.1186/s13024-017-0178-8

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