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Update on lichen planus and its clinical variants()

Lichen planus (LP) is an inflammatory skin condition with characteristic clinical and histopathological findings. Classic LP typically presents as pruritic, polygonal, violaceous flat-topped papules and plaques; many variants in morphology and location also exist, including oral, nail, linear, annul...

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Detalles Bibliográficos
Autores principales: Weston, Gillian, Payette, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418875/
https://www.ncbi.nlm.nih.gov/pubmed/28491978
http://dx.doi.org/10.1016/j.ijwd.2015.04.001
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author Weston, Gillian
Payette, Michael
author_facet Weston, Gillian
Payette, Michael
author_sort Weston, Gillian
collection PubMed
description Lichen planus (LP) is an inflammatory skin condition with characteristic clinical and histopathological findings. Classic LP typically presents as pruritic, polygonal, violaceous flat-topped papules and plaques; many variants in morphology and location also exist, including oral, nail, linear, annular, atrophic, hypertrophic, inverse, eruptive, bullous, ulcerative, lichen planus pigmentosus, lichen planopilaris, vulvovaginal, actinic, lichen planus-lupus erythematosus overlap syndrome, and lichen planus pemphigoides. Clinical presentation of the rarer variant lesions may be largely dissimilar to classic LP and therefore difficult to diagnose based solely on clinical examination. However, histopathological examination of LP and LP-variant lesions reveal similar features, aiding in the proper diagnosis of the disease. Management of LP and LP variants aims to control symptoms and to decrease time from onset to resolution; it often involves topical corticosteroids, but varies depending on the severity and location of the lesion. The literature contains an array of reports on the variations in presentation and successful management of LP and its variants. A familiarity with LP and its variants is important in achieving timely recognition and management of the disease.
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spelling pubmed-54188752017-05-10 Update on lichen planus and its clinical variants() Weston, Gillian Payette, Michael Int J Womens Dermatol Article Lichen planus (LP) is an inflammatory skin condition with characteristic clinical and histopathological findings. Classic LP typically presents as pruritic, polygonal, violaceous flat-topped papules and plaques; many variants in morphology and location also exist, including oral, nail, linear, annular, atrophic, hypertrophic, inverse, eruptive, bullous, ulcerative, lichen planus pigmentosus, lichen planopilaris, vulvovaginal, actinic, lichen planus-lupus erythematosus overlap syndrome, and lichen planus pemphigoides. Clinical presentation of the rarer variant lesions may be largely dissimilar to classic LP and therefore difficult to diagnose based solely on clinical examination. However, histopathological examination of LP and LP-variant lesions reveal similar features, aiding in the proper diagnosis of the disease. Management of LP and LP variants aims to control symptoms and to decrease time from onset to resolution; it often involves topical corticosteroids, but varies depending on the severity and location of the lesion. The literature contains an array of reports on the variations in presentation and successful management of LP and its variants. A familiarity with LP and its variants is important in achieving timely recognition and management of the disease. Elsevier 2015-09-16 /pmc/articles/PMC5418875/ /pubmed/28491978 http://dx.doi.org/10.1016/j.ijwd.2015.04.001 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Weston, Gillian
Payette, Michael
Update on lichen planus and its clinical variants()
title Update on lichen planus and its clinical variants()
title_full Update on lichen planus and its clinical variants()
title_fullStr Update on lichen planus and its clinical variants()
title_full_unstemmed Update on lichen planus and its clinical variants()
title_short Update on lichen planus and its clinical variants()
title_sort update on lichen planus and its clinical variants()
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418875/
https://www.ncbi.nlm.nih.gov/pubmed/28491978
http://dx.doi.org/10.1016/j.ijwd.2015.04.001
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