Cargando…
Update on lichen planus and its clinical variants()
Lichen planus (LP) is an inflammatory skin condition with characteristic clinical and histopathological findings. Classic LP typically presents as pruritic, polygonal, violaceous flat-topped papules and plaques; many variants in morphology and location also exist, including oral, nail, linear, annul...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418875/ https://www.ncbi.nlm.nih.gov/pubmed/28491978 http://dx.doi.org/10.1016/j.ijwd.2015.04.001 |
_version_ | 1783234135174676480 |
---|---|
author | Weston, Gillian Payette, Michael |
author_facet | Weston, Gillian Payette, Michael |
author_sort | Weston, Gillian |
collection | PubMed |
description | Lichen planus (LP) is an inflammatory skin condition with characteristic clinical and histopathological findings. Classic LP typically presents as pruritic, polygonal, violaceous flat-topped papules and plaques; many variants in morphology and location also exist, including oral, nail, linear, annular, atrophic, hypertrophic, inverse, eruptive, bullous, ulcerative, lichen planus pigmentosus, lichen planopilaris, vulvovaginal, actinic, lichen planus-lupus erythematosus overlap syndrome, and lichen planus pemphigoides. Clinical presentation of the rarer variant lesions may be largely dissimilar to classic LP and therefore difficult to diagnose based solely on clinical examination. However, histopathological examination of LP and LP-variant lesions reveal similar features, aiding in the proper diagnosis of the disease. Management of LP and LP variants aims to control symptoms and to decrease time from onset to resolution; it often involves topical corticosteroids, but varies depending on the severity and location of the lesion. The literature contains an array of reports on the variations in presentation and successful management of LP and its variants. A familiarity with LP and its variants is important in achieving timely recognition and management of the disease. |
format | Online Article Text |
id | pubmed-5418875 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-54188752017-05-10 Update on lichen planus and its clinical variants() Weston, Gillian Payette, Michael Int J Womens Dermatol Article Lichen planus (LP) is an inflammatory skin condition with characteristic clinical and histopathological findings. Classic LP typically presents as pruritic, polygonal, violaceous flat-topped papules and plaques; many variants in morphology and location also exist, including oral, nail, linear, annular, atrophic, hypertrophic, inverse, eruptive, bullous, ulcerative, lichen planus pigmentosus, lichen planopilaris, vulvovaginal, actinic, lichen planus-lupus erythematosus overlap syndrome, and lichen planus pemphigoides. Clinical presentation of the rarer variant lesions may be largely dissimilar to classic LP and therefore difficult to diagnose based solely on clinical examination. However, histopathological examination of LP and LP-variant lesions reveal similar features, aiding in the proper diagnosis of the disease. Management of LP and LP variants aims to control symptoms and to decrease time from onset to resolution; it often involves topical corticosteroids, but varies depending on the severity and location of the lesion. The literature contains an array of reports on the variations in presentation and successful management of LP and its variants. A familiarity with LP and its variants is important in achieving timely recognition and management of the disease. Elsevier 2015-09-16 /pmc/articles/PMC5418875/ /pubmed/28491978 http://dx.doi.org/10.1016/j.ijwd.2015.04.001 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Weston, Gillian Payette, Michael Update on lichen planus and its clinical variants() |
title | Update on lichen planus and its clinical variants() |
title_full | Update on lichen planus and its clinical variants() |
title_fullStr | Update on lichen planus and its clinical variants() |
title_full_unstemmed | Update on lichen planus and its clinical variants() |
title_short | Update on lichen planus and its clinical variants() |
title_sort | update on lichen planus and its clinical variants() |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418875/ https://www.ncbi.nlm.nih.gov/pubmed/28491978 http://dx.doi.org/10.1016/j.ijwd.2015.04.001 |
work_keys_str_mv | AT westongillian updateonlichenplanusanditsclinicalvariants AT payettemichael updateonlichenplanusanditsclinicalvariants |