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Nitric Oxide and Related Aspects Underlying Angina

Increased number of patients affected by metabolic syndrome (MS) has prompted the necessity of better understanding what is involved in such syndrome. Nevertheless, the establishment of promising therapies depends on the knowledge about the interaction of molecules within MS. In such context, Nitric...

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Detalles Bibliográficos
Autores principales: Restini, Carolina Baraldi Araujo, Gonçalves, Leticia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418930/
https://www.ncbi.nlm.nih.gov/pubmed/28567132
http://dx.doi.org/10.2174/1874192401711010033
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author Restini, Carolina Baraldi Araujo
Gonçalves, Leticia
author_facet Restini, Carolina Baraldi Araujo
Gonçalves, Leticia
author_sort Restini, Carolina Baraldi Araujo
collection PubMed
description Increased number of patients affected by metabolic syndrome (MS) has prompted the necessity of better understanding what is involved in such syndrome. Nevertheless, the establishment of promising therapies depends on the knowledge about the interaction of molecules within MS. In such context, Nitric Oxide (NO) emerges from a bulk of works relating its roles on aspects of MS, including cardiovascular diseases, their symptoms and comorbidities, which are thought to be triggered by similar sources. NO, nitric oxide synthase and enzymatic chains are keys for those disease and symptoms processes. NO has been separately described as part of hypertensive, ischemic and pain signaling. Although there are similar pathways likely shared for generating cardiovascular symptoms such angina, they are barely associated to NO in literature. The present review aims to clarify the patterns of NO alteration in metabolic syndrome directly concerned to cardiovascular symptoms, especially angina.
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spelling pubmed-54189302017-05-31 Nitric Oxide and Related Aspects Underlying Angina Restini, Carolina Baraldi Araujo Gonçalves, Leticia Open Cardiovasc Med J Article Increased number of patients affected by metabolic syndrome (MS) has prompted the necessity of better understanding what is involved in such syndrome. Nevertheless, the establishment of promising therapies depends on the knowledge about the interaction of molecules within MS. In such context, Nitric Oxide (NO) emerges from a bulk of works relating its roles on aspects of MS, including cardiovascular diseases, their symptoms and comorbidities, which are thought to be triggered by similar sources. NO, nitric oxide synthase and enzymatic chains are keys for those disease and symptoms processes. NO has been separately described as part of hypertensive, ischemic and pain signaling. Although there are similar pathways likely shared for generating cardiovascular symptoms such angina, they are barely associated to NO in literature. The present review aims to clarify the patterns of NO alteration in metabolic syndrome directly concerned to cardiovascular symptoms, especially angina. Bentham Open 2017-04-17 /pmc/articles/PMC5418930/ /pubmed/28567132 http://dx.doi.org/10.2174/1874192401711010033 Text en © 2017 Restini and Gonçalves. https://creativecommons.org/licenses/by/4.0/legalcode This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
Restini, Carolina Baraldi Araujo
Gonçalves, Leticia
Nitric Oxide and Related Aspects Underlying Angina
title Nitric Oxide and Related Aspects Underlying Angina
title_full Nitric Oxide and Related Aspects Underlying Angina
title_fullStr Nitric Oxide and Related Aspects Underlying Angina
title_full_unstemmed Nitric Oxide and Related Aspects Underlying Angina
title_short Nitric Oxide and Related Aspects Underlying Angina
title_sort nitric oxide and related aspects underlying angina
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418930/
https://www.ncbi.nlm.nih.gov/pubmed/28567132
http://dx.doi.org/10.2174/1874192401711010033
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