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Tacrine, Trolox and Tryptoline as Lead Compounds for the Design and Synthesis of Multi-target Agents for Alzheimer’s Disease Therapy

The versatile biological activities of tacrine, trolox and β-carboline derivatives make them promising lead structures for the development of multifunctional Alzheimer’s disease (AD) agents. Based on the topology of the active site of cholinesterases and other target proteins involved in the pathoge...

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Detalles Bibliográficos
Autores principales:	Teponnou, Gerard A. K., Joubert, Jacques, Malan, Sarel F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Open 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418947/ https://www.ncbi.nlm.nih.gov/pubmed/28567126 http://dx.doi.org/10.2174/1874104501711010024

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